Acne Severity (87% Improved)
Key Finding: 87% of participants had healed or notably improved acne after 4–5 weeks.
PMC: PMC3038963
Inflammatory Lesions & Gut–Acne Link (Mechanistic)
Key Finding: Saccharomyces boulardii significantly reduced inflammatory acne lesions and improved gut-related symptoms.
PubMed: 2530145
Gut–Brain–Skin Axis Mechanism Review
Key Insight: Probiotics reduce inflammation, support the gut barrier, and improve skin outcomes in acne sufferers.
Full Review PDF – PMC3038963
Improves Quality of Life in IBS Patients
Key Finding: S. boulardii significantly enhances quality of life in IBS patients beyond symptom relief.
PubMed: 21301358
Reduces SIBO and Digestive Symptoms in IBS-D
Key Finding: S. boulardii helps reduce SIBO and supports beneficial microbiota shifts in IBS-D.
PubMed: 36630947
Modulates Inflammation and Gut Histology in IBS-D
Key Finding: S. boulardii reduces inflammation and improves gut barrier health in IBS-D.
PubMed: 24722560
Supports Microbiota Regeneration After Diarrhea
Key Finding: S. boulardii CNCM I-745 significantly accelerates microbial recovery and reduces inflammation post-dysbiosis, supporting colonic barrier and microbiome balance.
PubMed: PMID: 26392857 | DOI: 10.2147/CEG.S85574
Prevents Recurrence of C. difficile Infection (CDI)
Key Finding: Co-administering S. boulardii reduced C. difficile relapse from 50% (placebo) to 16.7% in the vancomycin group.
PubMed: 7926463
Reduces Risk of CDI Relapse in High-Risk Patients
Key Finding: CDI recurrence was halved in high-risk patients receiving S. boulardii versus placebo (17% vs. 50%).
PubMed: 10763952
Maintains Microbiome Stability During Antibiotic Use
Key Finding: S. boulardii protected the gut microbiome during antibiotic treatment and prevented digestive side effects.
PubMed Abstract: 25234803
Improves Gut Microbiota in Short Bowel Syndrome (SBS)
Key Finding: S. boulardii enhanced microbial balance and reduced lactic acidosis risk in SBS patients.
PubMed: 25712934
Normalizes Stool Microbiota in Chronic Diarrhea
Key Finding: S. boulardii significantly restored microbiota structure and improved stool form in chronic diarrhea.
PubMed: 18416850