












Clear Gut, Clear Skin
Take 2 capsules daily in the morning on an empty stomach. For best results, take for at least 3 months.
Clear Gut, Clear Skin
Take 2 capsules daily in the morning on an empty stomach. For best results, take for at least 3 months.
Cerebiome® combined with Saccharomyces Boulardii CNCM I-1079, works to protect your gut microbiome and epithelial lining, improving gut discomforts, including gas and bloating, whilst creating a thriving microbial ecosystem
Probiotics with vitamin A strengthen the intestinal barrier, preventing harmful bacteria fragments from triggering inflammation and worsening skin conditions.
Cerebiome® increases levels of GABA (Gamma-Aminobutyric Acid), serotonin and dopamine. These neurotransmitters calm the brain promoting relaxation, reducing anxiety whilst enhancing our mental well-being and overall mood.
An imbalanced gut can trigger inflammation, oxidative stress, and skin issues like acne. S. boulardii supports gut balance and decreases LPS Levels for clearer skin, while Cerebiome® reduces stress, improves sleep, and enhances hydration, radiance, firmness, and elasticity.
Vitamins A and E strengthen antioxidant defenses, protect cell membranes, and prevent oxidative damage. Combined with Ahiflower® oil, they support mitochondrial function, redox balance, and optimal cellular protection.
Our probiotics lower pro-inflammatory cytokines, easing gut and brain inflammation. Cerebiome® also reduces LPS-related inflammation, supporting clearer skin and overall wellness.
Vitamin D regulates over 1,000 genes affecting mood, sleep, and hormones, while Ahiflower® oil’s essential fatty acids support hormone metabolism for healthier skin and balanced wellness.
Cerebiome® regulates the HPA axis to balance stress hormones, while Vitamin D and Safr’Inside™ support emotional balance, reduce irritability, and promote a positive mood.
Independent Studies on Clarify Within
Cerebiome ® Probiotic Blend
Reduces Stress-Related Gut Symptoms
Key finding: The supplement eased GI distress during stress.
PubMed: 19083380
Improves Mood & Reduces Anxiety
Key finding: Lowered anxiety (~25%), depression (~15%), and stress (~20%).
PubMed: 21983070
Improves Stress, Sleep, and Skin Appearance
Key finding: Cerebiome® supports the gut-brain-skin axis by improving mood and sleep while visibly enhancing skin quality.
Study link: PDF
Supports Mood and Increases BDNF in Mild-to-Moderate Depression
Key finding: Cerebiome® may improve depressive symptoms by increasing brain-derived neurotrophic factor (BDNF).
PubMed: 32989186
Enhances Anxiety Reduction in Health-Conscious Adults
Key finding: Cerebiome® may enhance emotional wellbeing when paired with healthy lifestyle behaviors.
Full Text: MDPI – Nutrients
Modulates Brain Activity Under Stress
Key finding: L. helveticus R0052 may influence stress-related brain activity, even without altering cortisol.
PubMed: 35405944
Improves Sleep Quality in Older Adults
Key finding: L. helveticus-fermented milk supports better sleep quality in elderly individuals.
PubMed: 1785146
Saccharomomyces Boulardii CNCM I-1079
Acne Severity (87% Improved)
Key Finding: 87% of participants had healed or notably improved acne after 4–5 weeks.
PMC: PMC3038963
Inflammatory Lesions & Gut–Acne Link (Mechanistic)
Key Finding: Saccharomyces boulardii significantly reduced inflammatory acne lesions and improved gut-related symptoms.
PubMed: 2530145
Gut–Brain–Skin Axis Mechanism Review
Key Insight: Probiotics reduce inflammation, support the gut barrier, and improve skin outcomes in acne sufferers.
Full Review PDF – PMC3038963
Improves Quality of Life in IBS Patients
Key Finding: S. boulardii significantly enhances quality of life in IBS patients beyond symptom relief.
PubMed: 21301358
Reduces SIBO and Digestive Symptoms in IBS-D
Key Finding: S. boulardii helps reduce SIBO and supports beneficial microbiota shifts in IBS-D.
PubMed: 36630947
Modulates Inflammation and Gut Histology in IBS-D
Key Finding: S. boulardii reduces inflammation and improves gut barrier health in IBS-D.
PubMed: 24722560
Supports Microbiota Regeneration After Diarrhea
Key Finding: S. boulardii CNCM I-745 significantly accelerates microbial recovery and reduces inflammation post-dysbiosis, supporting colonic barrier and microbiome balance.
PubMed: PMID: 26392857 | DOI: 10.2147/CEG.S85574
Prevents Recurrence of C. difficile Infection (CDI)
Key Finding: Co-administering S. boulardii reduced C. difficile relapse from 50% (placebo) to 16.7% in the vancomycin group.
PubMed: 7926463
Reduces Risk of CDI Relapse in High-Risk Patients
Key Finding: CDI recurrence was halved in high-risk patients receiving S. boulardii versus placebo (17% vs. 50%).
PubMed: 10763952
Maintains Microbiome Stability During Antibiotic Use
Key Finding: S. boulardii protected the gut microbiome during antibiotic treatment and prevented digestive side effects.
PubMed Abstract: 25234803
Improves Gut Microbiota in Short Bowel Syndrome (SBS)
Key Finding: S. boulardii enhanced microbial balance and reduced lactic acidosis risk in SBS patients.
PubMed: 25712934
Normalizes Stool Microbiota in Chronic Diarrhea
Key Finding: S. boulardii significantly restored microbiota structure and improved stool form in chronic diarrhea.
PubMed: 18416850
Safr'Inside
Improves Mood, Well-Being & Stress Response
Key finding: Saffron improved psychological resilience and subjective well-being under psychosocial stress.
ResearchGate Study Link
Rapid Stress Relief via Cortisol Modulation
Key finding: Safr'Inside™ rapidly modulates the HPA axis and lowers cortisol in response to acute stress.
PubMed: PMC10346743
Reduces Acute Stress Response in Healthy Young Men
Key finding: Safr’Inside™ reduces perceived stress and modulates cortisol response under acute stress.
PubMed: 37447245
Improves Mood, HRV, and Stress Resilience
Key finding: Safr’Inside™ improves mood, strengthens stress response, and increases HRV.
PubMed: 33598475
Improves Insomnia and Psychological Stress
Key finding: Safr’Inside™ improves sleep and reduces stress-related symptoms in adults with insomnia.
Study link 1
Study link 2
Enhances Sleep and Gut Microbiome in Older Adults
Key finding: Safr’Inside™ enhances sleep and supports SCFA-producing gut bacteria in older adults.
Study link
Vitamin A (Retinyl Palmitate)
Supports Skin Cell Function & Innate Immunity
Key finding: Vitamin A supports skin barrier defense and microbial homeostasis via TLR signaling.
PubMed: 33494277
Full text: PMC7909803
Synergistic Immune Modulation with Vitamin D
Key finding: Vitamins A and D cooperatively regulate immune tolerance, epithelial integrity, and balanced cytokine production.
PubMed: 33494277
Oral Vitamin A for Acne Treatment
Key finding: Oral vitamin A shows strong efficacy in treating acne across multiple trials.
PubMed: 35674761
Restores Gut Barrier in Deficiency
Key finding: Vitamin A is essential for maintaining intestinal barrier function and infection resistance.
PMC Full text: PMC6162863
Vitamin D3 (Veg D3®)
Highly Bioavailable Vegan Vitamin D₃
Key finding: VegD3® is a fast-acting, bioavailable vegan D₃ source equivalent to animal-derived cholecalciferol.
Study summary – AIDP announcement
Vegan-Friendly, Organic, and Potency-Resistant
Key fact: Provides a 1:1 plant-based alternative to lanolin-derived D₃ without loss of efficacy.
AIDP / Nutraceuticals World report
Regulates Skin Immune Function & Cell Proliferation
Key finding: VegD3® supports skin barrier health by balancing inflammatory T-cell responses.
Study link: Exploration Insightful Journals
Modulates Gut Microbiota Composition
Key finding: Oral VegD3® supplementation supports a healthier gut microbiome in a dose-responsive manner.
PubMed: 31892611
Supports Cognitive Function in Mild Cognitive Impairment
Key finding: VegD3® enhances cognition and genomic stability in older adults with MCI.
PubMed: 33164936
Vitamin E (as D-Alpha Tocopherol SunE 900)
Enhances Skin Photoprotection and Barrier Integrity
Key finding: Vitamin E is a powerful lipid-soluble antioxidant that reinforces skin defense against environmental stress.
PubMed: 17719081 (pubmed.ncbi.nlm.nih.gov)
Boosts Photoprotection via Oral Antioxidant Supplementation
Key finding: Oral vitamin E (with vitamin C) elevates MED and reduces UV-induced erythema.
PubMed: 9448204
Regulates Immune Function and Inflammation
Key finding: Vitamin E supports immune health and antioxidant defense at the cellular level.
PubMed: 17628169 (pubmed.ncbi.nlm.nih.gov)
Modulates T-Cell Function and Inflammatory Response
Key finding: Vitamin E improves adaptive immunity and reduces chronic inflammation.
PubMed: 30501009 (pubmed.ncbi.nlm.nih.gov)
Vitamin K2 (Vital K2®)
Gut Health & Microbiota Modulation
Key finding: Vitamin K supports gut barrier function and microbiome stability, reinforcing mucosal immunity.
DOI: 10.3389/fimmu.2021.791565
Cellular & Mitochondrial Health Benefits
Key finding: Vitamin K₂-7 is a multi-target compound that supports mitochondrial function, vascular protection, and anti-inflammatory resilience.
DOI: 10.3389/fphar.2022.896920
Improves Depression in PCOS Patients
Key finding: Vitamin K₂ may improve mood and emotional well-being in hormonally imbalanced populations.
PubMed: 35883082
Supports Mood Health & Cognitive Function
Key finding: Emerging evidence supports vitamin K’s role in mood regulation, cognitive performance, and neural health.
Full text: PMC128613079
Ahiflower® Oil
Boosts Circulating Omega-3s & Immune Modulation
Key finding: Increases anti-inflammatory omega-3 PUFAs and supports immune balance.
PubMed: 28287415
Outperforms Flaxseed Oil in EPA Conversion
Key finding: Ahiflower® converts more efficiently to EPA than flaxseed oil.
PMC: PMC4709838
Stearidonic Acid (SDA) Elevates EPA
Key finding: SDA is a superior omega-3 source for EPA synthesis.
DOI: 10.3389/fnut.2024.1359958
Gut Microbiome Modulation & Prebiotic Effect
Key finding: Supports a healthier microbiome and SCFA-linked gut–brain axis resilience.
PMC: PMC11067990
Enhances Probiotic Survival & SCFA Production
Key finding: Improves probiotic viability and butyrate/propionate production.
PMC: PMC9023356
Borage Oil
Rich in Antioxidants & Anti-Inflammatory Phytochemicals
Key finding: High GLA content and strong free radical scavenging activity linked to skin-calming effects.
Study link (DOI:10.3390/app13042560)
Improves Skin Barrier Function & Reduces Acne Lesions
Key finding: Borage oil improves skin hydration, strengthens barrier function, and reduces acne severity.
PubMed: 24553997

We shift the focus from treatment to prevention
Supplements alone aren’t a long-term fix. They nourish, balance, and restore from within — but without topical care, they can’t fully protect or strengthen the skin barrier. That’s why at Nourished3, we believe in integrating both: inner support through supplements and outer support through skincare.
Our supplements are powerful and clinically backed. The gut supplement supports microbiome diversity and reduces inflammation, while the brain supplement calms stress and restores balance. Together, they build a strong internal foundation for clear, radiant skin. But lasting transformation happens when supplements are paired with topical care — skincare that strengthens the barrier and amplifies internal results for visible, long-term clarity.
This philosophy is the foundation of our Trifecta Method™, designed to nourish the skin–gut–brain connection from every angle. It comes to life through our Triple Biotic™ Symbiotic Collection:
Step 1 (Skin): Postbiotic skincare, Step 2 (Gut): Probiotic gut supplement, Step 3 (Brain): Prebiotic brain supplement
Together, this system goes beyond surface or internal care alone — delivering truly holistic results that help your skin thrive, stay radiant, and flourish from the inside out.
Frequently asked questions
1. What is Clarify Within®?
Clarify Within® is a breakthrough supplement for clear, radiant skin that works through the skin–gut–brain axis™. It combines 6 billion CFUs of clinically studied probiotics, adaptogens, postbiotics, and plant-based omegas with essential vitamins and antioxidants to target breakouts, gut imbalances, and stress-related triggers from within.
2. How do I take it?
Adults 18+ should take two capsules daily in the morning on an empty stomach with a glass of water. For best results, use consistently for at least 3 months.
3. When will I see results?
Some users notice improvements in mood and gut comfort within 1–2 weeks, while skin clarity and hydration typically become more visible after 6–12 weeks of consistent use, in line with clinical studies on our key ingredients.
4. What makes Clarify Within® different from other supplements?
Unlike standard probiotics or acne supplements, Clarify Within® uses dual-capsule technology and Bio-Support™ stabilization to deliver active probiotics, fatty acids, and vitamins in their most effective form. The inner capsule delivers probiotics and adaptogens (Cerebiome®, Safr’Inside™, S. boulardii) directly to the gut, while the outer capsule releases omega oils and vitamins (A, D3, E, K2, Ahiflower®, Borage oil) for cellular and skin nourishment.
5. How long does one bottle last?
Each bottle contains 60 capsules, which is a 30-day supply.
6. Can I take Clarify Within® with other supplements?
Yes, Clarify Within® can be taken alongside most supplements. For the best results, we recommend combining it with:
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I SKIN (Clear Skin Collection skincare)
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III BRAIN (Calm Within® supplement)
Together, they provide comprehensive Skin–Gut–Brain Axis™ support through our Triple Biotic™ synergy system.
If you are on prescription medication, pregnant, or breastfeeding, consult your healthcare provider before use.
7. Is Clarify Within® pregnancy-safe?
If you are pregnant or breastfeeding, we recommend speaking with your doctor before use to ensure it is right for you.
8. Do I need to refrigerate it?
No. Thanks to its advanced dual-capsule design and Bio-Support™ technology, Clarify Within® is shelf-stable and does not require refrigeration. Store in a cool, dry place.
9. Does it contain allergens?
Clarify Within® is free from all 14 major allergens:
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celery
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cereals containing gluten (wheat, rye, barley, oats)
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crustaceans (prawns, crabs, lobsters)
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eggs
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fish
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lupin
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milk
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molluscs (mussels, oysters)
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mustard
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peanuts
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sesame
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soybeans
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sulphur dioxide and sulphites (>10 ppm)
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tree nuts (almonds, hazelnuts, walnuts, brazil nuts, cashews, pecans, pistachios, macadamias)
It is also free from artificial colors, added sugars, and GMOs, and is made to EU standards.
10. Is it vegan and cruelty-free?
Yes. Clarify Within® is 100% vegan, cruelty-free, and made without animal-derived ingredients, fillers, or contaminants.
11. Is the product Halal and Kosher?
Yes. All ingredients used in our supplements are Halal and Kosher certified.